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purpose. In order to evaluate the novel non-neurotoxic mode of action of the azole insecticide clofenac, and it is a promising alternative to conventional adult insecticides, which can fight against the fungus Anopheles.
method. A certain concentration of clofenacept raised in southern Africa with amphetamines is resistant to pyrethroids and susceptible to laboratory toxicity. Use standard WHO protocol to evaluate fungi and use probability analysis for analysis.
result. Compared with susceptible strains, pyrethroid-resistant strains showed consistently higher LD50 and LD95 values, but these differences were not statistically significant, and the amplitude was up to twice. The recorded LD50 value of An. The fungus is about three times higher than other Anopheles species.
in conclusion. Pyrethroid-resistant fungi based on monooxygenases will not affect the toxic effects of clofenac. It is impossible for An’s drug sensitivity to drop so small. Compared with other Anopheles mosquitoes, the fungus of fluclopirid will have any operational significance. Clofenazide is an important addition to the insecticide that can be used to control malaria vectors and can be used as a resistance management tool to avoid or slow down the development of resistance.
SV Oliver; Caesar (ML); Wood or Coetzee, M.; Rowland (Rowland) Brook, BD pyrrole insecticide clofenazin resistance to pyrethroids and susceptibility to Anopheles (Diptera: Culicidae) evaluation. Tropical Medicine and International Health (2010) 15 (1) 127-131. [DOI: 10.1111 / j.1365-3156.2009.02416.x]
Evaluation of the resistance and susceptibility of pyrrole insecticide clofenac to Anopheles to pyrethroids (Diptera: Cucurbitaceae).
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